Mutah Journal of Natural, Applied and Health Sciences

Linear Atrophoderma of Moulin: A Case Report Highlighting Response to Methotrexate

Ali Ratib Al –Sarayreh — 2025-12-31

Linear Atrophoderma of Moulin (LAM) is a rare dermatologic condition characterized by linear, hyperpigmented or hypopigmented atrophic lesions that follow Blaschko’s lines. Typically emerging in childhood or early adulthood, Linear Atrophoderma of Moulin remains poorly understood, with few cases reported in the literature. It is often misdiagnosed due to clinical overlap with other dermatoses, particularly Linear Morphea. While the disease is generally benign, it can cause cosmetic and functional issues. No standardized treatment exists, and therapeutic responses vary.

We report the case of a 22-year-old female who presented with a 17-year history of unilateral hyperpigmented and mildly atrophic patches on her left side, including the arm, breast, trunk, and leg. These lesions followed Blaschko’s lines and were accompanied by occasional calf pain and weakness. There was no history of inflammation, systemic symptoms, or relevant family history. Previous misdiagnoses included eczema and psoriasis, with no response to conventional treatments. A skin biopsy revealed basal layer hyperpigmentation, dermal collagen thickening, and perivascular lymphocytic infiltrates, supporting a diagnosis of Linear Atrophoderma of Moulin.

The patient was treated with oral methotrexate (20 mg weekly) and topical therapy consisting of betamethasone and calcipotriene. This treatment was maintained for one year under regular clinical monitoring.

The patient showed significant clinical improvement, including reduced calf pain, diminished weakness, and noticeable fading of hyperpigmented lesions, no new lesions developed during treatment. However, three months after discontinuation of methotrexate, new lesions appeared and symptoms recurred, highlighting the potential need for ongoing management in chronic cases.

This case emphasizes recognizing Linear Atrophoderma of Moulin as a distinct clinical entity and differentiating it from mimicking conditions such as Linear Morphea. Methotrexate, in combination with topical corticosteroid and vitamin D analog therapy, appears to offer a promising treatment option. Continued research is essential to establish effective, long-term treatment protocols.

Experimental investigation on ion separation using a ceramic Nanofiltration membrane: influence of trans-membrane pressure and solution concentration on ion rejection

Rasha A Hajarat — 2025-12-31

The current research intends to conduct an experimental work to study the removal efficiency of Magnesium (Mg²⁺), Potassium (K¹⁺), Sodium (Na¹⁺), Bromide (Br^1-) and Chloride (Cl^1-) ions from different prepared solutions using a ceramic Nanofiltration (NF) membrane with a molecular weight cut-off of 1 kDa. Specifically, the solutions are prepared using double ions and triple ions and the filtration is conducted using different operating conditions of the trans-membrane pressure (TMP) and ions concentrations. In this regard, the TMP ranges between 1 to 5 bar and the ion concentration ranged between 0.01 to 1.0 M (equivalent to 1.0 to 1000 mol/m³). The results demonstrate that the highest ion rejection can be attained with the maximum applied TMP. However, this is not the case for the NaBr and KBr solutions, demonstrating the reverse action. Variable ion rejection patterns are experimentally identified in the current research, which varies between 90% to 99.7%.

Forecasting the overall number of felony offenders in the State of Kuwait using time series models

Tareq Abdul-Aziz Aldoub — 2025-12-31

Time Series Analysis Techniques are fundamental in developing effective strategies for security planning, particularly in the field of crime prevention and control, as these methods significantly support security decision-making processes. This study aims to explore the application of time series models, with a focus on the ARIMA model, to forecast the total number of felony offenders in the State of Kuwait. The researcher relies on annual data published by the Research and Studies Center of Kuwait Ministry of Interior, covering the period from 1992 to 2022. The performance of various ARIMA models was evaluated using R-squared, Bayesian Information Criterion – Normalized (NBIC), and Root Mean Squared Error (RMSE) criteria. The study concluded that the optimal model is ARIMA (1,0,0). Based on this model, forecasts were made for the total number of felony offenders for the period from 2023 to 2030.

Caffeine consumption among university students in Jordan: a cross-sectional study using a self-administered online questionnaire

Aseel Abu Kayed — 2025-12-31

Caffeine is a naturally occurring stimulant from the methylxanthine family, and its consumption has notably increased among Arab youth. Despite this trend, empirical studies addressing caffeine consumption patterns among university students in Jordan remain limited. Therefore, this study aims to assess caffeine consumption patterns among Jordanian university students to evaluate their daily caffeine intake in relation to the safe intake level recommended by the European Food Safety Authority. A cross-sectional study was conducted, using a questionnaire structured via Google Forms, and distributed randomly through social media platforms. A total of 400 participants were recruited and completed the questionnaire between March and May 2025. The results showed that the students consumed products containing caffeine. Caffeine consumption was more prevalent among females (70.1%) than among males (29.9%). Coffee was the primary contributor to caffeine intake for both males and females. Participants reported consuming caffeine mainly to enhance academic performance (50.7%), for its unique flavor (50.1%), and to overcome drowsiness (46%). Overall, 46.8% of the participants reported daily caffeine consumption exceeding the safe level of caffeine (400 mg/day). These findings indicate that a considerable percentage of university students consume caffeine at high levels, highlighting the need for awareness and educational initiatives to warn students about the potential health consequences of excessive caffeine consumption.